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This article Coronavirus: exempt emergency vaccines from late-stage clinical trials, Chinese health official urges WHO first appeared on South China Morning PostДЇor the latest news from the South China Morning Post download our mobile app. What next for Chinese coronavirus vaccines after WHO approves first two products? Of the 21 Chinese vaccines at the human trials stage, eight, including the ones that have been approved for general use and have emergency use authorisation in China, are conducting human trials and one is in the process of overseas regulatory approval for a phase 3 trial.Д¬hina approves Covid-19 vaccine for children as young as threeД¬hina pushes to expand Covid-19 vaccine development but more work needed on trials: health officialД¬oronavirus: Singapore residents look to Sinovac shot as alternative to mRNA vaccines This involves tens of thousands of participants and is a process described by industry insiders as long, expensive and challenging.

China pushes to expand vaccine development with 20 candidates in trialsД«ut since China has now largely contained Covid-19, the country cannot test vaccines within its own borders and must instead conduct phase 3 trials overseas. In the early stage of the pandemic, China responded with vaccine development using different technologies starting as early as February last year, including the more advanced mRNA platform.

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Mainland researchers such as Zhu Fengcai, deputy director of the Jiangsu Centre for Disease Prevention and Control, have been studying to how to use surrogate endpoint data from immunity of Covid-19 vaccines that have released trials results to predict the protection of Covid-19 vaccines. вЂњFor vaccines with good results from animal trials, phase 1/2 clinical trials and the production in full compliance with good manufacturing standards, considerations should be made to exempt phase 3 clinical trials and using neutralising antibodies as an alternative indicator, and that could significantly increase the supplies of Covid-19 vaccines.вЂќД¬onfidence in Covid-19 vaccines could be affected if a correlate that is not very rigorous was chosen or the vaccine did not work as well as expected, the meeting was told.

вЂњWe also advocate that the WHO make timely adjustments to the rules for listing emergency use for Covid-19 vaccines in light of the actual situation of global epidemic prevention and control,вЂќ Zeng was quoted as saying by state news agency Xinhua late on Sunday. Zeng Yixin, vice-minister of the National Health Commission, said the WHO should consider replacing phase 3 human trials with data relating to neutralising antibody levels вЂ“ an indicator of immunity вЂ“ generated by the vaccines under consideration to scale up production.Дo you have questions about the biggest topics and trends from around the world? Get the answers with SCMP Knowledge, our new platform of curated content with explainers, FAQs, analyses and infographics brought to you by our award-winning team. The call comes days after a second Chinese Covid-19 vaccine was granted the listing.

A senior Chinese health official has called on the World Health Organization to scrap late-stage human trials as a criterion for its coronavirus vaccine emergency use listing.